Gonadal germ cell tumors in children and adolescents
نویسندگان
چکیده
منابع مشابه
Gonadal germ cell tumors in children
BACKGROUND The true incidence of gonadal germ cell tumors (GCTs) in children is unknown. Few studies have been published concerning about pediatric gonadal GCTs. The aim of this study is to review and analyze clinical data on the diagnosis and management of gonadal GCTs in children. METHODS Between 2005 and 2015, 127 pediatric patients (<14 years old) with gonadal GCTs admitted to our institu...
متن کامل[Germ cell tumors in children and adolescents].
3.7% of the diagnoses in the Pediatric Tumour Registry (Zentrales Tumor-Register) of the German Society for Pediatric Oncology and Haematology (Gesellschaft für Pädiatrische Onkologie und Hämatologie) concern germ cell tumors. The annual incidence has increased from 0.22 in 1980 to 0.60 per 100,000 children in 1992. The most common localizations are the coccygeal region (25%), followed by the t...
متن کاملBiology and Molecular Markers of Malignant Gonadal Germ Cell Tumors
5 Original Publications 8 Abbreviations 9 Introduction 10 Review of the Literature 11 1. Germ cells 11 1.1 Inner cell mass and embryonic stem cells 11 1.2 Factors essential for maintenance of pluripotency and self-renewal 11 1.3 Development and migration of germ cells 14 2. Gonadal development 16 2.1 Ovarian differ entiation 17 2.2 Testicular differentiation 18 3. GATA transcription factors in ...
متن کاملSurvival of Children with Germ Cell Tumors in Ali Asghar Hospital since 1990 to 2003
Background and Objective: Germ cell tumor (GCT) accounts for approximately 2-3% of all malignancies in children. In this respect, about 20% of patients with GCT are still resistant to therapy. Materials and Methods: The cross-sectional strategy of this survey was undertaken on 57 patients with germ cell ...
متن کاملCell for Gonadal and Nongonadal Pediatric Germ Cell Tumors Multipoint Imprinting Analysis Indicates a Common Precursor
Pediatric germ cell tumors (GCTs) commonly arise at extragonadal sites. It has been proposed that nongonadal GCTs arise from ectopic primordial germ cells that have aberrantly migrated during embryogenesis. During a time between their migration and development to mature gametes, primordial germ cells are characterized by their lack of imprinting, which can be assessed by the evaluation of allel...
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ژورنال
عنوان ژورنال: Journal of Indian Association of Pediatric Surgeons
سال: 2014
ISSN: 0971-9261
DOI: 10.4103/0971-9261.141995